Selected Publications
Showing 242 of 242 publications
- H GALGAT, N Pouya, M NIKOLAOU, Using Machine Learning to Design Effective Antimicrobial Dosing Regimens. Computers & Chemical Engineering, 109645, 2026. [View on Google Scholar]
- BM Eales, J Smith, N Pouya, CS Hudson, VH Tam, M Nikolaou, Rapid design of combination antimicrobial therapy against Acinetobacter baumannii. Computers & chemical engineering 192, 108884, 2025. [View on Google Scholar]
- G Singh, SG Mohiuddin, S Ghosh, J Narzary, MA Orman, M Nikolaou, Systematic design of pulse dosing to eradicate persister bacteria: The case of fluoroquinolones. Computers & chemical engineering 195, 109010, 2025. [View on Google Scholar]
- M Nikolaou, Recent developments and prospects of machine learning in chemical engineering. Reviews in Chemical Engineering 41 (4), 309-310, 2025. [View on Google Scholar]
- S Barua, JE Smith, VH Tam, M Nikolaou, Enhancing the Time-to-Positivity Paradigm for Guidance of Antimicrobial Therapy: A Model-Based Approach. Computers & chemical engineering, 109325, 2025. [View on Google Scholar]
- MH Mukhtar, M Nikolaou, C Ehlig-Economides, Categorizing Legacy Wellbores in the Delaware Basin Based on Failure Risks Under Wastewater Injection. SPE Annual Technical Conference and Exhibition, D021S030R006, 2025. [View on Google Scholar]
- S Barua, VH Tam, M Nikolaou, Enhancing the Time-to-Positivity (TTP) Paradigm for the Design of Effective Combination Therapy: A Computer-Aided Approach. 2025 AIChE Annual Meeting, 2025. [View on Google Scholar]
- KK Rao, M Nikolaou, Y Yao, CM Wolverton, LC Grabow, Discovery of Lithium Solid State Electrolytes through Machine Learned Probability Density Analysis. Electrochemical Society Meeting Abstracts prime2024, 1054-1054, 2024. [View on Google Scholar]
- G Singh, MA Orman, JC Conrad, M Nikolaou, Systematic design of pulse dosing to eradicate persister bacteria. PLoS Computational Biology 19 (1), e1010243, 2023. [View on Google Scholar]
- M Nikolaou, VH Tam, I KESISOGLOU, Optical based methods for determining antimicrobial dosing regimens. US Patent App. 17/636,079, 2023. [View on Google Scholar]
- M Nikolaou, VH Tam, Rapid In Vitro Assessment of Antimicrobial Drug Effect Bridging Clinically Relevant Pharmacokinetics: A Comprehensive Methodology. Pharmaceutics 15 (6), 1671, 2023. [View on Google Scholar]
- CS Hudson, JE Smith, BM Eales, M Nikolaou, VH Tam, In vitro model to simulate multiple drugs with distinct elimination half-lives. International journal of antimicrobial agents 62 (4), 106924, 2023. [View on Google Scholar]
- M Nikolaou, Ziegler and Nichols meet Kermack and McKendrick: Parsimony in dynamic models for epidemiology. Computers & Chemical Engineering 157, 107615, 2022. [View on Google Scholar]
- I Kesisoglou, VH Tam, AP Tomaras, M Nikolaou, Discerning in vitro pharmacodynamics from OD measurements: A model-based approach. Computers & chemical engineering 158, 107617, 2022. [View on Google Scholar]
- M Nikolaou, Revisiting the standard for modeling the spread of infectious diseases. Scientific reports 12 (1), 7077, 2022. [View on Google Scholar]
- C Ehlig-Economides, M Nikolaou, MA Khan, Methodology to Estimate Low Grade Enhanced Geothermal System (EGS) Reserves Using Heat Extracted from Depleted Wells in High Temperature Shale Gas Formations. SPE Annual Technical Conference and Exhibition?, D011S020R002, 2022. [View on Google Scholar]
- I Kesisoglou, VH Tam, M Nikolaou, Deciphering Longitudinal Optical-Density Measurements to Guide Antibiotic Use: A Model Based Approach. 2022 AIChE Annual Meeting, 2022. [View on Google Scholar]
- G Singh, M Orman, J Conrad, M Nikolaou, Trick and Treat: Pulse Dosing to Eradicate Persister Bacteria. 2022 AIChE Annual Meeting, 2022. [View on Google Scholar]
- I Kesisoglou, BM Eales, PR Merlau, VH Tam, M Nikolaou, Deciphering longitudinal optical-density measurements to guide clinical dosing regimen design: A model-based approach. Computer methods and programs in biomedicine 227, 107212, 2022. [View on Google Scholar]
- VH Tam, H Abodakpi, W Wang, KR Ledesma, PR Merlau, K Chan, ..., Optimizing pharmacokinetics/pharmacodynamics of β-lactam/β-lactamase inhibitor combinations against high inocula of ESBL-producing bacteria. Journal of Antimicrobial Chemotherapy 76 (1), 179-183, 2021. [View on Google Scholar]
- G Luo, C Ehlig-Economides, M Nikolaou, Advantage of miscible fluid injection and tight oil production through a single-well alternating production-injection procedure over other single-well EOR methods. Journal of Petroleum Science and Engineering 199, 108091, 2021. [View on Google Scholar]
- I Kesisoglou, G Singh, M Nikolaou, The Lambert function should be in the engineering mathematical toolbox. Computers & chemical engineering 148, 107259, 2021. [View on Google Scholar]
- S Gupta, M Nikolaou, L Saputelli, C Bravo, System and method for detecting, diagnosing, and correcting trips or failures of electrical submersible pumps. US Patent 11,078,774, 2021. [View on Google Scholar]
- L Zeinali, C Ehlig-Economides, M Nikolaou, Enhanced Geothermal System Model for Flow through a Stimulated Rock Volume. SPE Annual Technical Conference and Exhibition?, D021S040R004, 2021. [View on Google Scholar]
- BM Eales, CS Hudson, I Kesisoglou, W Wang, M Nikolaou, VH Tam, Experimental Validation of a Mathematical Framework to Simulate Antibiotics with Distinct Half-Lives Concurrently in an In Vitro Model. Antibiotics 10 (10), 1256, 2021. [View on Google Scholar]
- I Kesisoglou, VH Tam, AP Tomaras, M Nikolaou, Discerning in Vitro Pharmacodynamics from Optical Density Measurements: A Model-Based Approach. 2021 AIChE Annual Meeting, 2021. [View on Google Scholar]
- KK Rao, Y Yao, M Nikolaou, CM Wolverton, L Grabow, Automated Solid State Electrolyte Conductivity Predictions Via Probability Density Analysis. 2021 AIChE Annual Meeting, 2021. [View on Google Scholar]
- I Kesisoglou, BM Eales, KR Ledesma, PR Merlau, VH Tam, W Wang, ..., Simultaneous in vitro simulation of multiple antimicrobial agents with different elimination half-lives in a pre-clinical infection model. Computers & chemical engineering 155, 107540, 2021. [View on Google Scholar]
- M Nikolaou, Simple Formulas for a Two-Tier Strategy to Flatten the Curve. arXiv preprint arXiv:2004.04271, 2020. [View on Google Scholar]
- M Nikolaou, Using feedback on symptomatic infections to contain the coronavirus epidemic: Insight from a SPIR model. medRxiv, 2020.04. 14.20065698, 2020. [View on Google Scholar]
- M Nikolaou, A fundamental inconsistency in the sir model structure and proposed remedies. medRxiv, 2020.04. 26.20080960, 2020. [View on Google Scholar]
- F Alwarda, G Liu, M Nikolaou, C Ehlig-Economides, Automated procedure for quantifying ISIP and friction losses from stage by stage hydraulic fracture treatment falloff data. SPE Annual Technical Conference and Exhibition?, D031S036R004, 2020. [View on Google Scholar]
- KK Rao, M Nikolaou, Y Yao, L Grabow, Machine Learning the Fundamental Tradeoffs between Conductivity and Voltage Stability in Solid State Electrolytes. 2020 Virtual AIChE Annual Meeting, 2020. [View on Google Scholar]
- G Mijares, A Garcia, S Sankaran, J Rodriguez, L Saputelli, A Awasthi, ..., Systems and methods for optimization of real time production operations. US Patent 10,354,207, 2019. [View on Google Scholar]
- G Luo, C Ehlig-Economides, M Nikolaou, A Control Methodology for CO2 Injection to Optimize Tight Oil Production from a Fractured Horizontal Well. 2019 AIChE Annual Meeting, 2019. [View on Google Scholar]
- G Luo, C Ehlig-Economides, M Nikolaou, Optimizing Tight Oil Recovery through a Single Well Alternating Production-Injection Procedure. 2019 AIChE Annual Meeting, 2019. [View on Google Scholar]
- G Luo, C Ehlig-Economides, M Nikolaou, Optimization of Single-Well CO2 Injection for Enhancement of Tight Oil Production. 2018 AIChE Annual Meeting, 2018. [View on Google Scholar]
- S Mathur, M Marongiu-Porcu, M Nikolaou, Predicting Future Production for Unconventional Resources: A Data-Driven Approach. 2018 AIChE Annual Meeting, 2018. [View on Google Scholar]
- J Rodrigues, M Nikolaou, Geosteering Using Image Logs and an Intelligent Bottomhole Assembly. 2018 AIChE Annual Meeting, 2018. [View on Google Scholar]
- S Misra, M Nikolaou, A data-driven modeling approach to zonal isolation of cemented gas wells. Journal of Natural Gas Science and Engineering 59, 262-273, 2018. [View on Google Scholar]
- N Goyal, M Marongiu-Porcu, M Nikolaou, Estimating the Drainage Area of. 2018 AIChE Annual Meeting, 2018. [View on Google Scholar]
- A Khanal, M Khoshghadam, WJ Lee, M Nikolaou, New forecasting method for liquid rich shale gas condensate reservoirs with data driven approach using principal component analysis. Journal of Natural Gas Science and Engineering 38, 621-637, 2017. [View on Google Scholar]
- KH Macfarlan, CP Wreden, MJ Schinnell, M Nikolaou, A comparative hydraulic analysis of conventional-and reverse-circulation primary cementing in offshore wells. SPE Drilling & Completion 32 (01), 59-68, 2017. [View on Google Scholar]
- S Misra, M Nikolaou, Adaptive design of experiments for model order estimation in subspace identification. Computers & Chemical Engineering 100, 119-138, 2017. [View on Google Scholar]
- S Misra, M Darby, S Panjwani, M Nikolaou, Design of experiments for control-relevant multivariable model identification: an overview of some basic recent developments. Processes 5 (3), 42, 2017. [View on Google Scholar]
- M Eden, M Nikolaou, CAST Director's Student Presentation Award Finalists. 2017 AIChE Annual Meeting, 2017. [View on Google Scholar]
- S Misra, M Nikolaou, Design of Experiments for Identification of Model That Is Suitable for Use in Control System. 2017 AIChE Annual Meeting, 2017. [View on Google Scholar]
- S Panjwani, J McDaniel, M Nikolaou, Improvement of zonal isolation in horizontal shale gas wells: A data-driven model-based approach. Journal of Natural Gas Science and Engineering 47, 101-113, 2017. [View on Google Scholar]
- AP Singh, M Nikolaou, L Saputelli, M Maucec, Methods and systems for reservoir history matching for improved estimation of reservoir performance. US Patent App. 14/770,381, 2016. [View on Google Scholar]
- S Bhattacharya, M Nikolaou, Comprehensive optimization methodology for stimulation design of low-permeability unconventional gas reservoirs. Spe Journal 21 (03), 0947-0964, 2016. [View on Google Scholar]
- S Panjwani, M Nikolaou, Experiment design for control‐relevant identification of partially known stable multivariable systems. AIChE Journal 62 (9), 2986-3001, 2016. [View on Google Scholar]
- S Panjwani, M Nikolaou, Ensuring integral controllability for robust multivariable control. Computers & Chemical Engineering 92, 172-179, 2016. [View on Google Scholar]
- S Gupta, M Nikolaou, L Saputelli, C Bravo, ESP health monitoring KPI: a real-time predictive analytics application. SPE Intelligent Energy International Conference and Exhibition, SPE-181009-MS, 2016. [View on Google Scholar]
- S Gupta, L Saputelli, M Nikolaou, Applying big data analytics to detect, diagnose, and prevent impending failures in electric submersible pumps. SPE Annual Technical Conference and Exhibition?, D031S038R004, 2016. [View on Google Scholar]
- S Gupta, L Saputelli, M Nikolaou, Big data analytics workflow to safeguard ESP operations in real-time. SPE Artificial Lift Conference and Exhibition-Americas, D021S004R003, 2016. [View on Google Scholar]
- PR Bhagunde, M Nikolaou, VH Tam, Modeling heterogeneous bacterial populations exposed to antibiotics: The logistic‐dynamics case. AIChE Journal 61 (8), 2385-2393, 2015. [View on Google Scholar]
- Y Lin, HY Wang, S He, M Nikolaou, Increasing shale gas recovery through thermal stimulation: analysis and an experimental study. SPE Annual Technical Conference and Exhibition?, D021S018R008, 2015. [View on Google Scholar]
- AP Singh, M Nikolaou, Optimal rules for central bank interest rates subject to zero lower bound. Economics: The Open-Access, Open-Assessment E-Journal 8 (2014-37), 1-67, 2014. [View on Google Scholar]
- ML Darby, M Nikolaou, Identification test design for multivariable model-based control: An industrial perspective. Control Engineering Practice 22, 165-180, 2014. [View on Google Scholar]
- VH Tam, M Nikolaou, High Throughput Screening for Antimicrobial Dosing Regimens. US Patent App. 13/899,876, 2014. [View on Google Scholar]
- AP Singh, S Mukherjee, M Nikolaou, Debottlenecking level control for tanks in series. Journal of Process Control 24 (3), 158-171, 2014. [View on Google Scholar]
- HB Siahaan, EH Vefring, M Nikolaou, JE Gravdal, Evaluation of Coordinated Control During Back Pressure MPD Operations. SPE Norway Subsurface Conference, SPE-169205-MS, 2014. [View on Google Scholar]
- C Wreden, JT Watters, R Giroux, M Nikolaou, K Macfarlan, DA Richardson, Deepwater reverse-circulation primary cementing: Applicability and technical path forward for implementation. Offshore Technology Conference, D031S030R002, 2014. [View on Google Scholar]
- C Bravo, L Saputelli, F Rivas, AG Pérez, M Nikolaou, G Zangl, ..., State of the art of artificial intelligence and predictive analytics in the E&P industry: a technology survey. Spe Journal 19 (04), 547-563, 2014. [View on Google Scholar]
- MW Tan, DC Lye, TM Ng, M Nikolaou, VH Tam, Mathematical model to quantify the effects of risk factors on carbapenem-resistant Acinetobacter baumannii. Antimicrobial Agents and Chemotherapy 58 (9), 5239-5244, 2014. [View on Google Scholar]
- S Panjwani, M Nikolaou, Ensuring Environmental Friendliness of Horizontal Shale Gas Wells Through Zonal Isolation: A Model-Based Approach (554b). AIChE Annual Meeting. San Francisco, CA, 2013. [View on Google Scholar]
- LA Carlsen, G Nygaard, M Nikolaou, Evaluation of control methods for drilling operations with unexpected gas influx. Journal of Process Control 23 (3), 306-316, 2013. [View on Google Scholar]
- AP Singh, M Nikolaou, Control of a process with unmeasured disturbances that change its steady-state gain sign. Journal of Process Control 23 (3), 294-305, 2013. [View on Google Scholar]
- G Mijares, A Garcia, S Sankaran, J Rodriguez, L Saputelli, A Awasthi, ..., Systems and methods for optimization of real time production operations. US Patent 8,396,826, 2013. [View on Google Scholar]
- M Nikolaou, Computer-aided process engineering in oil and gas production. Computers & chemical engineering 51, 96-101, 2013. [View on Google Scholar]
- VH Tam, M Nikolaou, High throughput screening for antimicrobial dosing regimens. US Patent 8,452,543, 2013. [View on Google Scholar]
- J Bassett*, J Watters, NK Combs, M Nikolaou, Lowering drilling cost, improving operational safety, and reducing environmental impact through zonal isolation improvements for horizontal wells drilled in the marcellus shale. Global Meeting Abstracts, 1020-1028, 2013. [View on Google Scholar]
- L Saputelli, B Cesar, N Michael, L Carlos, R Cramer, M Toshi, G Moricca, Best practices and lessons learned after 10 years of digital oilfield (DOF) implementations. SPE Kuwait Oil and Gas Show and Conference, SPE-167269-MS, 2013. [View on Google Scholar]
- S Bhattacharya, M Nikolaou, Analysis of production history for unconventional gas reservoirs with statistical methods. SPE Journal 18 (05), 878-896, 2013. [View on Google Scholar]
- M Nikolaou, X Wang, MJ Economides, Optimisation of compressed natural gas marine transportation with composite-Material containers. SPE Asia Pacific Oil and Gas Conference and Exhibition, SPE-165898-MS, 2013. [View on Google Scholar]
- I Øyvind Breyholtz, M Nikolaou, Drilling Automation: Presenting a Framework for Automated Operations. . [View on Google Scholar]
- Ø Breyholtz, M Nikolaou, Drilling automation: Presenting a framework for automated operations. SPE Drilling & Completion 27 (01), 118-126, 2012. [View on Google Scholar]
- C Bravo, L Saputelli, F Rivas, AG Perez, M Nikolaou, G Zangl, ..., State-of-the-art application of artificial intelligence and trends in the E&P industry: A technology survey. SPE Intelligent Energy International, 2012. [View on Google Scholar]
- ML Darby, M Nikolaou, MPC: Current practice and challenges. Control Engineering Practice 20 (4), 328-342, 2012. [View on Google Scholar]
- B Guo, K Abdelraouf, KR Ledesma, M Nikolaou, VH Tam, Predicting bacterial fitness cost associated with drug resistance. Journal of antimicrobial chemotherapy 67 (4), 928-932, 2012. [View on Google Scholar]
- P Bhagunde, KT Chang, EB Hirsch, KR Ledesma, M Nikolaou, VH Tam, Novel modeling framework to guide design of optimal dosing strategies for β-lactamase inhibitors. Antimicrobial agents and chemotherapy 56 (5), 2237-2240, 2012. [View on Google Scholar]
- S Bhattacharya, M Nikolaou, MJ Economides, Unified Fracture Design for very low permeability reservoirs. Journal of Natural Gas Science and Engineering 9, 184-195, 2012. [View on Google Scholar]
- VH Tam, M Nikolaou, A novel approach to pharmacodynamic assessment of antimicrobial agents: new insights to dosing regimen design. PLoS computational biology 7 (1), e1001043, 2011. [View on Google Scholar]
- P Bhagunde, R Singh, KR Ledesma, KT Chang, M Nikolaou, VH Tam, Modelling biphasic killing of fluoroquinolones: guiding optimal dosing regimen design. Journal of antimicrobial chemotherapy 66 (5), 1079-1086, 2011. [View on Google Scholar]
- Ø Breyholtz, G Nygaard, M Nikolaou, Managed-pressure drilling: Using model predictive control to improve pressure control during dual-gradient drilling. SPE Drilling & Completion 26 (02), 182-197, 2011. [View on Google Scholar]
- ML Darby, M Nikolaou, J Jones, D Nicholson, RTO: An overview and assessment of current practice. Journal of Process control 21 (6), 874-884, 2011. [View on Google Scholar]
- MJ Economides, M Nikolaou, Technologies for oil and gas production: present and future. AIChE journal 57 (8), 1974-1982, 2011. [View on Google Scholar]
- P Diomede, M Nikolaou, DJ Economou, Voltage waveform to achieve a desired ion energy distribution on a substrate in contact with plasma. Plasma Sources Science and Technology 20 (4), 045011, 2011. [View on Google Scholar]
- B Guo, K Abdelraouf, KR Ledesma, KT Chang, M Nikolaou, VH Tam, Quantitative impact of neutrophils on bacterial clearance in a murine pneumonia model. Antimicrobial agents and chemotherapy 55 (10), 4601-4605, 2011. [View on Google Scholar]
- S Bhattacharya, M Nikolaou, Optimal fracture spacing and stimulation design for horizontal wells in unconventional gas reservoirs. SPE Annual Technical Conference and Exhibition?, SPE-147622-MS, 2011. [View on Google Scholar]
- GJ Moridis, H Kuzma-Anderson, MT Reagan, TA Blasingame, R Santos, ..., A Self-Teaching Expert System for the Analysis, Design, and Prediction of Gas Production from Unconventional Gas Resources. Society of Petroleum Engineers, 2011. [View on Google Scholar]
- S Bhattacharya, M Nikolaou, Using data from existing wells to plan new wells in unconventional gas field development. SPE Canada Unconventional Resources Conference, SPE-147658-MS, 2011. [View on Google Scholar]
- GJ Moridis, HA Kuzma, MT Reagan, TA Blasingame, YW Huang, ..., SeTES: a self-teaching expert system for the analysis, design, and prediction of gas production from unconventional gas resources. SPE Canada Unconventional Resources Conference, SPE-149485-MS, 2011. [View on Google Scholar]
- WJ Foster, N Dowla, SY Joshi, M Nikolaou, The fluid mechanics of scleral buckling surgery for the repair of retinal detachment. Graefe's Archive for Clinical and Experimental Ophthalmology 248 (1), 31-36, 2010. [View on Google Scholar]
- M Nikolaou, Optimizing the logistics of compressed natural gas transportation by marine vessels. Journal of Natural Gas Science and Engineering 2 (1), 1-20, 2010. [View on Google Scholar]
- Ø Breyholtz, G Nygaard, H Siahaan, M Nikolaou, Managed pressure drilling: A multi-level control approach. SPE Intelligent Energy International Conference and Exhibition, SPE-128151-MS, 2010. [View on Google Scholar]
- K Abrams, KS Buchanan, MA Case, D NeJaime, SK Katyal, T Ruskola, All Rights Reserved.. . [View on Google Scholar]
- Ø Breyholtz, G Nygaard, M Nikolaou, Automatic control of managed pressure drilling. Proceedings of the 2010 American Control Conference, 442-447, 2010. [View on Google Scholar]
- P Bhagunde, KT Chang, R Singh, V Singh, KW Garey, M Nikolaou, ..., Mathematical modeling to characterize the inoculum effect. Antimicrobial agents and chemotherapy 54 (11), 4739-4743, 2010. [View on Google Scholar]
- HA Kuzma, K Boyle, S Pullman, MT Reagan, GJ Moridis, TA Blasingame, ..., SeTES, a Self-Teaching Expert System for the analysis, design and prediction of gas production from shales and a prototype for a new generation of Expert Systems in the Earth …. AGU Fall Meeting Abstracts 2010, IN53A-1155, 2010. [View on Google Scholar]
- JE Gravdal, M Nikolaou, Ø Breyholtz, LA Carlsen, Improved kick management during MPD by real-time pore-pressure estimation. SPE Drilling & Completion 25 (04), 577-584, 2010. [View on Google Scholar]
- ML Darby, M Harmse, M Nikolaou, MPC: Current practice and challenges. IFAC Proceedings Volumes 42 (11), 86-98, 2009. [View on Google Scholar]
- ML Darby, M Nikolaou, Multivariable System Identification for Integral Controllability–Computational Issues. IFAC Proceedings Volumes 42 (11), 452-457, 2009. [View on Google Scholar]
- M Nikolaou, M Economides, X Wang, M Marongiu-Porcu, SS: CNG Transportation Technology in 2009. Distributed Compressed Natural Gas Sea Transport. Offshore Technology Conference, OTC-19738-MS, 2009. [View on Google Scholar]
- ML Darby, M Nikolaou, Multivariable system identification for integral controllability. Automatica 45 (10), 2194-2204, 2009. [View on Google Scholar]
- Ø Breyholtz, G Nygaard, M Nikolaou, Advanced automatic control for dual-gradient drilling. SPE Annual Technical Conference and Exhibition?, SPE-124631-MS, 2009. [View on Google Scholar]
- ML Darby, M Nikolaou, Design of experiments for identification of multivariable models satisfying integral controllability: The dynamic model case. AIChE annual meeting. paper 240d, 2008. [View on Google Scholar]
- M Nikolaou, Development and experimental testing of a new approach to modeling the effect of antimicrobial agents on heterogeneous microbial populations. NSF Award Number 0730454. Directorate for Engineering 7 (730454), 30454, 2008. [View on Google Scholar]
- M Nikolaou, VH Tam, Combating microbial resistance to antimicrobial agents through dosing regimen optimization. Optimization in Medicine and Biology, 2008. [View on Google Scholar]
- GJ Lim, EK Lee, Optimization in medicine and biology. Auerbach Publications, 2008. [View on Google Scholar]
- LA Carlsen, G Nygaard, JE Gravdal, M Nikolaou, J Schubert, Performing the dynamic shut-in procedure because of a kick incident when using automatic coordinated control of pump rates and choke-valve opening. SPE/IADC Managed Pressure Drilling and Underbalanced Operations Conference …, 2008. [View on Google Scholar]
- A Awasthi, S Sankaran, M Nikolaou, L Saputelli, G Mijares, Meeting the Challenges of Real Time Production Optimization—A Parametric Model-based Approach. SPE Intelligent Energy International Conference and Exhibition, SPE-111853-MS, 2008. [View on Google Scholar]
- A Awasthi, S Sankaran, M Nikolaou, L Saputelli, G Mijares, Short-term production optimization by automated adaptive modeling and control. SPE Intelligent Energy International Conference and Exhibition, SPE-112239-MS, 2008. [View on Google Scholar]
- TP Lim, KR Ledesma, KT Chang, JG Hou, AL Kwa, M Nikolaou, JP Quinn, ..., Quantitative Assessment of Combination Antimicrobial Therapy against Multidrug-Resistant Acinetobacter baumannii. Antimicrobial agents and chemotherapy 52 (8), 2898-2904, 2008. [View on Google Scholar]
- VH Tam, KR Ledesma, G Vo, S Kabbara, TP Lim, M Nikolaou, Pharmacodynamic Modeling of Aminoglycosides against Pseudomonas aeruginosa and Acinetobacter baumannii: Identifying Dosing Regimens To Suppress …. Antimicrobial agents and chemotherapy 52 (11), 3987-3993, 2008. [View on Google Scholar]
- VH Tam, G Vo, S Kabbara, M Nikolaou, O423 Pharmacodynamics of gentamicin against Pseudomonas aeruginosa: modelling bacterial response to drug-selective pressures. International Journal of Antimicrobial Agents 29, S87-S88, 2007. [View on Google Scholar]
- A Awasthi, S Sankaran, M Nikolaou, L Saputelli, G Mijares, Closing the Gap Between Reservoir Simulation and Production Optimization. SPE Digital Energy Conference and Exhibition, SPE-107463-MS, 2007. [View on Google Scholar]
- ML Darby, M Nikolaou, A parametric programming approach to moving-horizon state estimation. Automatica 43 (5), 885-891, 2007. [View on Google Scholar]
- M Nikolaou, Model predictive controllers: A critical synthesis of theory and industrial needs. Advances in Chemical Engineering 26, 133, 2007. [View on Google Scholar]
- M Nikolaou, AN Schilling, G Vo, K Chang, VH Tam, Modeling of microbial population responses to time-periodic concentrations of antimicrobial agents. Annals of Biomedical Engineering 35 (8), 1458-1470, 2007. [View on Google Scholar]
- ML Darby, M Nikolaou, Design of experiments for multivariable systems subject to integral controllability. AIChE annual meeting. paper 143i, 2007. [View on Google Scholar]
- A Awasthi, M Nikolaou, S Sankaran, L Saputelli, G Mijares, Real-Time Production Optimization Using" Proxy Models". The 2007 Annual Meeting, 2007. [View on Google Scholar]
- VH Tam, AN Schilling, K Poole, M Nikolaou, Mathematical modelling response of Pseudomonas aeruginosa to meropenem. Journal of antimicrobial chemotherapy 60 (6), 1302-1309, 2007. [View on Google Scholar]
- M Nikolaou, VH Tam, Quantitative Assessment of Biofitness in Heterogeneous Bacterial Populations under Antibiotic Pressure. The 2006 Annual Meeting, 2006. [View on Google Scholar]
- A Awasthi, M Nikolaou, Controlling Weight-on-Bit near Its Optimum in Hydrocarbon Drilling Operations Using a Linear Model Predictive Control with State Estimation. The 2006 Annual Meeting, 2006. [View on Google Scholar]
- J Wang, QP He, AL Tuskegee, On State Estimation in the Low-Volume High-MIX Semiconductor Manufacturing Using a Singular Gauss-Markov Model. The 2006 Annual Meeting, 2006. [View on Google Scholar]
- NT Mittadar, M Nikolaou, DJ Economou, Building Non-Parametric Models for Rsm: a Bayesian Approach and Its Application to Plasma Etching. The 2006 Annual Meeting, 2006. [View on Google Scholar]
- M Nikolaou, VH Tam, A new modeling approach to the effect of antimicrobial agents on heterogeneous microbial populations. Journal of mathematical biology 52 (2), 154-182, 2006. [View on Google Scholar]
- MJ Economides, WFJ Deeg, P Valko, M Nikolaou, S Sankaran, Method for stress and stability related measurements in boreholes. US Patent 7,006,918, 2006. [View on Google Scholar]
- L Saputelli, M Nikolaou, MJ Economides, Real-time reservoir management: A multiscale adaptive optimization and control approach. Computational Geosciences 10 (1), 61-96, 2006. [View on Google Scholar]
- M Nikolaou, AS Cullick, L Saputelli, Production optimization—a moving-horizon approach. SPE Intelligent Energy International Conference and Exhibition, SPE-99358-MS, 2006. [View on Google Scholar]
- M Nikolaou, AS Cullick, L Saputelli, G Mijares, S Sankaran, L Reis, A Consistent Approach Toward Reservoir Simulation at Different Time Scales. SPE Intelligent Energy International Conference and Exhibition, SPE-99451-MS, 2006. [View on Google Scholar]
- M Nikolaou, Control of snack food manufacturing systems. IEEE Control Systems Magazine 26 (4), 40-53, 2006. [View on Google Scholar]
- VH Tam, Mathematical modelling of resistance emergence. Journal of Antimicrobial Chemotherapy 56 (5), 983-983, 2005. [View on Google Scholar]
- NT Mittadar, DJ Economou, M Nikolaou, J Yi, S McClatchie, P Yadav, ..., Using high fidelity simulation in the design of experiments for optimizing etch uniformity in plasma etching reactors. 05AIChE: 2005 AIChE Annual Meeting and Fall Showcase, 2005. [View on Google Scholar]
- VH Tam, AN Schilling, M Nikolaou, Modelling time–kill studies to discern the pharmacodynamics of meropenem. Journal of antimicrobial chemotherapy 55 (5), 699-706, 2005. [View on Google Scholar]
- M Nikolaou, P Misra, VH Tam, AD Bailey III, Complexity in semiconductor manufacturing, activity of antimicrobial agents, and drilling of hydrocarbon wells: Common themes and case studies. Computers & chemical engineering 29 (11-12), 2266-2289, 2005. [View on Google Scholar]
- ML Darby, M Nikolaou, A Parametric Approach to Moving Horizon Constrained State Estimation. The 2005 Annual Meeting, 2005. [View on Google Scholar]
- M Nikolaou, AS Cullick, L Saputelli, Oilfield-Wide Optimization. The 2005 Annual Meeting, 2005. [View on Google Scholar]
- A Awasthi, M Nikolaou, Model Predictive Control of Weight-on-Bit near Its Optimum in Hydrocarbon Well Drilling: the Value of Constraints. The 2005 Annual Meeting, 2005. [View on Google Scholar]
- L Saputelli, M Nikolaou, MJ Economides, Self-learning reservoir management. SPE Reservoir Evaluation & Engineering 8 (06), 534-547, 2005. [View on Google Scholar]
- M Nikolaou, VH Tam, Dynamics of Heterogeneous Bacterial Populations under Antimicrobial Agent Pressure: The Case of Regrowth. Journal of Pharmacokinetics and Pharmacodynamics, submitted, 2004. [View on Google Scholar]
- MJ Economides, WFJ Deeg, P Valko, M Nikolaou, S Sankaran, System and method for stress and stability related measurements in boreholes. US Patent 6,834,233, 2004. [View on Google Scholar]
- M Nikolaou, Adaptive Design of Experiments for Optimal Uniformity in Semiconductor Manufacturing. NSF Award Number 0227232. Directorate for Engineering 2 (227232), 27232, 2003. [View on Google Scholar]
- P Misra, M Nikolaou, Input design for model order determination in subspace identification. AIChE Journal 49 (8), 2124-2132, 2003. [View on Google Scholar]
- M Nikolaou, P Misra, Linear control of nonlinear processes: recent developments and future directions. Computers & chemical engineering 27 (8-9), 1043-1059, 2003. [View on Google Scholar]
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- M Nikolaou, Model predictive controllers: A critical synthesis of theory and industrial needs. Academic Press 26, 131-204, 2001. [View on Google Scholar]
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- M Nikolaou, Model Predictive Controllers: A Critical Synthesis of Theory and Industrial Needs-VA Theory for MPC with Predictable Properties-B Robust Stability and Fragility of Constrained MPC. Advances in Chemical Engineering 26, 176-184, 2001. [View on Google Scholar]
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- M Nikolaou, Process Measurement and Control: Industry Needs 6–8 March 1998 Sheraton New Orleans Hotel: Workshop on Identification and Adaptive Control. Computers & chemical engineering 23 (2), 217-227, 1998. [View on Google Scholar]
- M Nikolaou, Computer-aided process engineering in the snack food industry. AIChE symposium series 93 (316), 61-70, 1997. [View on Google Scholar]
- M Nikolaou, Design of Constrained Model-Predictive Control Systems with Increased Autonomy. NSF Award Number 9615979. Directorate for Engineering 96 (9615979), 15979, 1997. [View on Google Scholar]
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- M Nikolaou, Y You, Use of wavelets for numerical solution of differential equations. Wavelet Applications in Chemical Engineering, 209-274, 1994. [View on Google Scholar]
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- JY Fan, M Nikolaou, RE White, An approach to fault diagnosis of chemical processes via neural networks. AIChE Journal 39 (1), 82-88, 1993. [View on Google Scholar]
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- M Nikolaou, V Hanagandi, Control of nonlinear dynamical systems modeled by recurrent neural networks. AIChE journal 39 (11), 1890-1894, 1993. [View on Google Scholar]
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- M Nikolaou, A hybrid approach to the analysis and design of control systems for nonlinear processes. University of California, Los Angeles, 1989. [View on Google Scholar]
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- E Olanrewaju, M Wen, M Nikolaou, Machine Learning Zeolite Synthesis Conditions. 2025 AIChE Annual Meeting, 0. [View on Google Scholar]